(±)-HIP-A
Product Specifications
UNSPSC Description
(±)-HIP-A is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-A is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-A can be used in the study of neurological diseases[1].
Target Antigen
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-hip-a.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H]1[C@]2([H])[C@](ONC2=O)([H])CN1)=O
Molecular Weight
172.14
References & Citations
[1]Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107525/racemic-HIP-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107525/
Clinical Information
No Development Reported
CAS Number
227619-64-9
Curated Selection
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