(S) -3,4-DCPG
(S) -3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8[1].
Product Specifications
CAS Number
201730-11-2
Product Name Alternative
(S) -3,4-Dicarboxyphenylglycine
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-3-4-dcpg.html
Purity
99.9
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O
Molecular Formula
C10H9NO6
Molecular Weight
239.18
Precautions
H302, H312, H332
References & Citations
[1]Thomas NK, et al. (S) -3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 2001 Mar;40 (3) :311-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR8
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