(S) -3,4-DCPG

(S) -3,4-DCPG is a selective agonist of metabotropic glutamate receptor 8a (mGluR8a) with an EC50 of 31 nM in AV12-664 cells expressing human mGluR8[1].

Product Specifications

CAS Number

[201730-11-2]

Product Name Alternative

(S) -3,4-Dicarboxyphenylglycine

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-3-4-dcpg.html

Purity

99.9

Solubility

DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O

Molecular Formula

C10H9NO6

Molecular Weight

239.18

Precautions

H302, H312, H332

References & Citations

[1]Thomas NK, et al. (S) -3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 2001 Mar;40 (3) :311-8.