Diftalone

Diftalone (Aladione) is an anti-inflammatory agent. Diftalone can be used for research of inflammatory disease, such as rheumatoid arthritis[1].

Product Specifications

CAS Number

[21626-89-1]

Product Name Alternative

Aladione; L 5418

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/diftalone.html

Solubility

10 mM in DMSO

Smiles

O=C1N2N(CC3=CC=CC=C13)C(C4=C(C=CC=C4)C2)=O

Molecular Formula

C16H12N2O2

Molecular Weight

264.28

References & Citations

[1]Della Porta G, et al. Carcinogenic activity in mice of diftalone, an anti-inflammatory agent. J Cancer Res Clin Oncol. 1984;108 (3) :308-11.|[2]Chalem F, et al. Diftalone: a new non-steroidal anti-inflammatory agent: comparative study with phenylbutazone in the treatment of rheumatoid arthritis. J Int Med Res. 1977;5 (1) :18-25.