Hyzetimibe
Hyzetimibe is a cholesterol absorption inhibitor. Hyzetimibe blocks the intestinal absorption of cholesterol and phytol. Hyzetimibe is well tolerated in animal models, with an LDmax 2000 mg/kg in rats and an LDmax 500 mg/kg in rhesus monkeys[1].
Product Specifications
CAS Number
[1266548-74-6]
Product Name Alternative
HS-25
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hyzetimibe.html
Solubility
10 mM in DMSO
Smiles
OC/C(C1=CC=C(C=C1)F)=C\C[C@@H]2[C@](C3=CC=C(C=C3)O)([H])N(C4=CC=C(C=C4)F)C2=O
Molecular Formula
C25H21F2NO3
Molecular Weight
421.44
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107176A/Hyzetimibe-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107176A/
Scientific Category
Reference compound1
Clinical Information
Phase 3
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