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MT-7716 (free base)

MT-7716 free base (W-212393) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention[1].

Product Specifications

CAS Number

610323-32-5

Product Name Alternative

W-212393

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mt-7716-free-base.html

Solubility

10 mM in DMSO

Smiles

O=C(CN(C1=O)C2=CC=CC=C2N1C3CCN(CC3)[C@@H]4CC5=C6C4=CC=CC6=CC=C5)NC

Molecular Formula

C27H28N4O2

Molecular Weight

440.54

References & Citations

[1]de Guglielmo G, et al, MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats. Addict Biol. 2015 Jul;20 (4) :643-51.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NOP Receptor/ORL1

Frequently Asked Questions

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