Tazomeline

Tazomeline is a selective M1 muscarinic receptor agonist. Tazomeline inhibits twitch height in rabbit vas deferens (IC50= 0.001 nM) . Tazomeline can be used for research of neuropsychiatric disorders[1].

Product Specifications

CAS Number

131987-54-7

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tazomeline.html

Solubility

10 mM in DMSO

Smiles

CCCCCCSC1=NSN=C1C2=CCCN(C)C2

Molecular Formula

C14H23N3S2

Molecular Weight

297.48

References & Citations

[1]Sauerberg P, et al. Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3- (1,2,5-thiadiazolyl) -1,2,5,6-tetrahydro-1-methylpyridines . J Med Chem. 1992 Jun 12;35 (12) :2274-83.