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Lirequinil

Lirequinil (Ro 41-3696) is an orally active partial agonist of the benzodiazepine (BDZ) receptor. Lirequinil has the effect of promoting sleep[1].

Product Specifications

CAS Number

[143943-73-1]

Product Name Alternative

Ro 41-3696

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lirequinil.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C[C@@H](OCC)CC1)C2=C3C4=C(C=CC(Cl)=C4)CCN3C(C(C5=CC=CC=C5)=C2)=O

Molecular Formula

C26H25ClN2O3

Molecular Weight

448.94

References & Citations

[1]M Tsuboi, et al. Changes in mouse hippocampal EEG characteristics after oral administration of Ro 41-3696, nitrazepam, or zopiclone alone and in combination with ethanol. Pharmacology. 1994 Nov;49 (5) :278-85.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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