GE 2270A
Product Specifications
UNSPSC Description
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2].
Target Antigen
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ge-2270a.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CSC(C3=CC=C(C4=NC(C5=N[C@@H](CO5)C(N6[C@@H](CCC6)C(N)=O)=O)=CS4)N=C3C7=CSC(C8=CSC([C@](NC(CNC(C9=C(SC([C@@H](NC(C%10=C(C)SC([C@@H](N1)CC(NC)=O)=N%10)=O)C(C)C)=N9)COC)=O)=O)([H])[C@H](C%11=CC=CC=C%11)O)=N8)=N7)=N2
Molecular Weight
1290.52
References & Citations
[1]Landini P, B et al. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. Biochem J. 1992 May 1;283 ( Pt 3)(Pt 3):649-52.|[2]Anborgh PH, Parmeggiani A. New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu. EMBO J. 1991 Apr;10(4):779-84.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106882/GE-2270A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106882/
Clinical Information
No Development Reported
CAS Number
134861-34-0
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