GE 2270A

GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2].

Product Specifications

CAS Number

[134861-34-0]

Product Name Alternative

MDL 62879

UNSPSC

12352209

Target

Antibiotic; Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ge-2270a.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CSC(C3=CC=C(C4=NC(C5=N[C@@H](CO5)C(N6[C@@H](CCC6)C(N)=O)=O)=CS4)N=C3C7=CSC(C8=CSC([C@](NC(CNC(C9=C(SC([C@@H](NC(C%10=C(C)SC([C@@H](N1)CC(NC)=O)=N%10)=O)C(C)C)=N9)COC)=O)=O)([H])[C@H](C%11=CC=CC=C%11)O)=N8)=N7)=N2

Molecular Formula

C56H55N15O10S6

Molecular Weight

1290.52

References & Citations

[1]Landini P, B et al. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin. Biochem J. 1992 May 1;283 (Pt 3) (Pt 3) :649-52.|[2]Anborgh PH, Parmeggiani A. New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu. EMBO J. 1991 Apr;10 (4) :779-84.