Almokalant
Almokalant is a class III antiarrhythmic agent, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
Product Specifications
CAS Number
123955-10-2
Product Name Alternative
H 234/09
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Almokalant.html
Solubility
10 mM in DMSO
Smiles
CCCS(CCCN(CC)CC(O)COC1=CC=C(C#N)C=C1)=O
Molecular Formula
C18H28N2O3S
Molecular Weight
352.49
References & Citations
[1]Wellfelt K, et al. Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species. Reprod Toxicol. 1999 Mar-Apr;13 (2) :93-101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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