Amitivir

Amitivir (LY 217896), a thiadiazole derivative, possesses broad antiviral activity against orthomyxo- and paramyxoviruses. Amitivir is effective against influenza A and B viruses[1][2].

Product Specifications

CAS Number

[111393-84-1]

Product Name Alternative

LY 217896

UNSPSC

12352005

Hazard Statement

H302-H312-H315-H319-H332-H335

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/amitivir.html

Solubility

10 mM in DMSO

Smiles

N#CNC1=NN=CS1

Molecular Formula

C3H2N4S

Molecular Weight

126.14

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Hayden FG, et al. Oral LY217896 for prevention of experimental influenza A virus infection and illness in humans. Antimicrob Agents Chemother. 1994;38 (5) :1178-1181.|[2]Colacino JM, et al. Evaluation of the anti-influenza virus activities of 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and its sodium salt. Antimicrob Agents Chemother. 1990;34 (11) :2156-2163.