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Ajoene

Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].

Product Specifications

CAS Number

[92285-01-3]

UNSPSC

12352100

Hazard Statement

H225, H319, H336

Target

Apoptosis; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/ajoene.html

Concentration

21.33 mM * 200 μL in Ethyl acetate

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=S(C/C=C/SSCC=C)CC=C

Molecular Formula

C9H14OS3

Molecular Weight

234.40

Precautions

H225, H319, H336

References & Citations

[1]Taylor P, et al. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239 (2) :298-304. |[2]Ahmed N, et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res. 2001;21 (5) :3519-3523.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-106784/Ajoene-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-106784/Ajoene-SDS-MedChemExpress.pdf

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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