SCH 900978
SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression[1].
Product Specifications
CAS Number
873947-10-5
Product Name Alternative
NK-1 Antagonist 1
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/sch-900978.html
Solubility
10 mM in DMSO
Smiles
C[C@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@@]2(C3=CC=CC=C3)CC[C@](C#N)(N4C(NN=C4)=O)CN2
Molecular Formula
C25H23F6N5O2
Molecular Weight
539.47
References & Citations
[1]Jane H. Hsiao, et al. Heteroaryl carbonitriles for the treatment of disease. WO2017011445A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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