Proglumetacin
Proglumetacin is an orally active and potent cyclo-oxygenase inhibitor. Proglumetacin can inhibits SARS-CoV Mpro (main protease of the SARS-CoV-2), with an AC50 of 8.9 μM (activity concentration at half maximal activity) . Proglumetacin has anti-inflammatory activity, can be used for inflammation (such as Rheumatoid arthritis, and Allergic air pouch inflammation) research[1][2][3].
Product Specifications
CAS Number
[57132-53-3]
UNSPSC
12352005
Target
COX; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/proglumetacin.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OCCN4CCN(CCCOC(CCC(C(N(CCC)CCC)=O)NC(C5=CC=CC=C5)=O)=O)CC4
Molecular Formula
C46H58ClN5O8
Molecular Weight
844.43
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106560/Proglumetacin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106560/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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