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Protizinic acid

Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM[1][2].

Product Specifications

CAS Number

13799-03-6

UNSPSC

12352005

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/protizinic-acid.html

Solubility

10 mM in DMSO

Smiles

CN1C2=C(C=CC(C(C)C(O)=O)=C2)SC3=CC(OC)=CC=C13

Molecular Formula

C17H17NO3S

Molecular Weight

315.39

References & Citations

[1]K Suzuki, et al. Effects of protizinic acid on leukokinin generation and its physiological action. Agents Actions. 1984 Jun;14 (5-6) :699-706.|[2]H Ohnishi, et al. Effects of protizinic acid on the prostaglandins system and the production of oxygen radicals. Nihon Yakurigaku Zasshi. 1982 Jun;79 (6) :561-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Phospholipase A

Frequently Asked Questions

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