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Enprostil

Enprostil (RS 84135) is a prostaglandin E2 derivative. Enprostil can inhibit amogastrin-stimulated gastric acid secretion, as well as reducing the secretion of pepsin. Enprostil can also serve as an antiulcer agent, used for research of duodenal or gastric ulcers[1][2].

Product Specifications

CAS Number

73121-56-9

Product Name Alternative

RS 84135

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/enprostil.html

Solubility

10 mM in DMSO

Smiles

O[C@H](COC1=CC=CC=C1)/C=C/[C@H]2[C@@H](C(C[C@@H]2O)=O)CC=C=CCCC(OC)=O

Molecular Formula

C23H28O6

Molecular Weight

400.46

References & Citations

[1]Kohli Y, et al. Antisecretory effect of a PGE2 derivative, enprostil (TA/RS-84135) : inhibitory action of amogastrin-stimulated secretion. Drugs Exp Clin Res. 1988;14 (11) :673-8. |[2]Goa K L, et al. Enprostil: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of peptic ulcer disease[J]. Drugs, 1987, 34 (5) : 539-559.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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