JAK-2/3-IN-1
Product Specifications
UNSPSC Description
JAK-2/3-IN-1 is a potent JAK-2 and JAK-3 inhibitor extracted from patent US8163732B2, compound 46, has Kis of [1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak-2-3-in-1.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C2=NC3=CC=CC=C3C4=C5C(NC=C25)=NC=C4)C(Cl)=C1
Molecular Weight
345.78
References & Citations
[1]Youssef Bennani, et al. Tricyclic heteroaryl compounds useful as inhibitors of Janus kinase. US8163732B2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10652/JAK-2-3-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10652/
Clinical Information
No Development Reported
CAS Number
1036241-36-7
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