Tosagestin
Tosagestin (Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].
Product Specifications
CAS Number
[110072-15-6]
Product Name Alternative
Org 30659
UNSPSC
12352211
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tosagestin.html
Solubility
10 mM in DMSO
Smiles
C[C@]1(C2)[C@](C=C[C@@]1(O)C#C)([H])[C@@]3([H])[C@]([C@]4([H])C(CC3)=CC(CC4)=O)([H])C2=C
Molecular Formula
C21H24O2
Molecular Weight
308.41
References & Citations
[1]Schoonen WG, et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Mol Biol. 1995;55 (3-4) :439-444. 、|[2]Obruca A, et al. Ovarian function during and after treatment with the new progestagen Org 30659. Fertil Steril. 2001;76 (1) :108-115.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106297/Tosagestin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106297/
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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