Tosagestin

Tosagestin (Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].

Product Specifications

CAS Number

[110072-15-6]

Product Name Alternative

Org 30659

UNSPSC

12352211

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tosagestin.html

Solubility

10 mM in DMSO

Smiles

C[C@]1(C2)[C@](C=C[C@@]1(O)C#C)([H])[C@@]3([H])[C@]([C@]4([H])C(CC3)=CC(CC4)=O)([H])C2=C

Molecular Formula

C21H24O2

Molecular Weight

308.41

References & Citations

[1]Schoonen WG, et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Mol Biol. 1995;55 (3-4) :439-444. 、|[2]Obruca A, et al. Ovarian function during and after treatment with the new progestagen Org 30659. Fertil Steril. 2001;76 (1) :108-115.