Ketotrexate (sodium)
Product Specifications
UNSPSC Description
Ketotrexate sodium is an orally active antifolate and immunosuppressant. Ketotrexate sodium has good anti-inflammatory activity and is widely used in rheumatoid arthritis (RA). Ketotrexate sodium is used in research into cancer and autoimmune diseases[1][2].
Target Antigen
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ketotrexate-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(CC[C@H](NC(C1=CC=C(C=C1)NCCC2N(C3=C(NC2)NC(N)=NC3=O)C)=O)C(O[Na])=O)O[Na]
Molecular Weight
517.45
References & Citations
[1]Puig L. Methotrexate: new therapeutic approaches. Actas Dermosifiliogr. 2014 Jul-Aug;105(6):583-9. |[2]Torres RP, et al. Methotrexate: Implications of pharmacogenetics in the treatment of patients with Rheumatoid Arthritis. ARP Rheumatol. 2022 Oct 1;1(3):225-229.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105934A/Ketotrexate-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105934A/
Clinical Information
No Development Reported
CAS Number
52386-42-2
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