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Butanserin

Butanserin (R 53393) is a potent and selective α1-adrenoceptor antagonist for the study of cardiovascular disease[1].

Product Specifications

CAS Number

87051-46-5

Product Name Alternative

R 53393

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/butanserin.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCCCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C4=CC=CC=C4NC1=O

Molecular Formula

C24H26FN3O3

Molecular Weight

423.48

References & Citations

[1]Korstanje C, et al. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-, alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-, alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38 (5) :374-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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