Butanserin
Butanserin (R 53393) is a potent and selective α1-adrenoceptor antagonist for the study of cardiovascular disease[1].
Product Specifications
CAS Number
87051-46-5
Product Name Alternative
R 53393
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/butanserin.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCCCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C4=CC=CC=C4NC1=O
Molecular Formula
C24H26FN3O3
Molecular Weight
423.48
References & Citations
[1]Korstanje C, et al. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-, alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-, alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38 (5) :374-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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