Mazaticol
Product Specifications
UNSPSC Description
Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].
Target Antigen
mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mazaticol.html
Solubility
10 mM in DMSO
Smiles
CC1(C)[C@H](N(C)[C@H](CC1)C2)C[C@@H]2OC(C(C3=CC=CS3)(C4=CC=CS4)O)=O
Molecular Weight
405.57
References & Citations
[1]Niimi Y, et al. Mazaticol for Treating Parkinson. 2020.|[2]Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69(3):261-270.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105793/Mazaticol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105793/
Clinical Information
No Development Reported
CAS Number
42024-98-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7179047 Inquire
Rabbit anti-Saccharomyces cerevisiae (strain Lalvin EC1118/Prise de mousse)(Baker's yeast) VRG4 Polyclonal Antibody
Ask
View Details 
MBS2020640-01 24 Strip Well
Mouse Wingless Type MMTV Integration Site Family, Member 10B (WNT10B) ELISA Kit
Ask
View Details MBS2020640-02 48 Well
Mouse Wingless Type MMTV Integration Site Family, Member 10B (WNT10B) ELISA Kit
Ask
View Details