Trenimon
Trenimon is a compound with anti-cancer effects. Trenimon shows mutagenic actions in many species by inducing point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Trenimon can be used for the research of cancer[1][2][3][4].
Product Specifications
CAS Number
68-76-8
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trenimon.html
Solubility
10 mM in DMSO
Smiles
O=C1C(N2CC2)=C(N3CC3)C(C(N4CC4)=C1)=O
Molecular Formula
C12H13N3O2
Molecular Weight
231.25
References & Citations
[1]Linford JH. 2,3,5-Tris-ethylenimino-1,4-benzoquinone (Trenimon) : some chemical and biological properties. Chem Biol Interact. 1973 Mar;6 (3) :149-68.|[2]GRUNICKE H, et al. THE EFFECTS OF THE ALKYLATING CYTOSTATIC AGENT, 2,3,5-TRISETHYLENEIMINO-BENZOQUINONE-1,4 (TRENIMON), ON THE PRIMING ABILITY OF DNA FROM MOUSE-ASCITES-TUMOR CELLS IN THE RNA-POLYMERASE-SYSTEM. Biochem Biophys Res Commun. 1965 Feb 3;18:319-24.|[3]Wegehaupt S, Sehrbundt HJ. Cytologische Untersuchungen an HeLa-Zellen nach kurzfristigen 2,3,5-Trisathyleniminobenzochinon-1,4-Gaben (Trenimon-R) [Cytologic studies on HeLa cells following short-spaced doses of 2,3,5-trisethyleniminobenzoquinone-1,4 (Trenimon-R) ]. Naturwissenschaften. 1967 Mar;54 (5) :123. German.|[4]Obe G, Beek B. Trenimon: biochemical, physiological and genetic effects on cells and organisms. Mutat Res. 1979 Mar;65 (1) :21-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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