TGX-155
TGX-155 (AZ12649385) is a selective inhibitor of PI3Kβ. TGX-155 has potential applications in antithrombotic therapy[1][2][3].
Product Specifications
CAS Number
[351071-90-4]
Product Name Alternative
AZ12649385
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tgx-155.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=CC(OC3=C(C=C(F)C=C3)C)=C2NC(N4CCOCC4)=C1
Molecular Formula
C20H19FN2O3
Molecular Weight
354.37
References & Citations
[1]Verheijen J C, et al. Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs[J]. Drugs Future, 2007, 32 (6) : 537-547.|[2]Nylander S, et al. Human target validation of phosphoinositide 3-kinase (PI3K) β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor. J Thromb Haemost. 2012 Oct;10 (10) :2127-36.|[3]Sturgeon SA, et al. Adaptation of the Folts and electrolytic methods of arterial thrombosis for the study of anti-thrombotic molecules in small animals. J Pharmacol Toxicol Methods. 2006 Jan-Feb;53 (1) :20-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105666/TGX-155-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105666/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kβ
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![(2Z) -2-[ (3,4-Dimethoxyphenyl) imino]-7-hydroxy-N- (tetrahydrofuran-2-ylmethyl) -2H-chromene-3-carboxamide](https://cdn.genprice.uk/genprice/genprice3.png)
sc-491800 5 mg
(2Z) -2-[ (3,4-Dimethoxyphenyl) imino]-7-hydroxy-N- (tetrahydrofuran-2-ylmethyl) -2H-chromene-3-carboxamide
Ask
View Details 
MBS1171269 Inquire
Recombinant Treponema pallidum Nuclease sbcCD subunit C (sbcC), partial
Ask
View Details 
ASE-9706-4 1 Kit
IPSC-Derived Myoblasts With Media (Normal, Male, Caucasian, Adult, From Fibroblasts)
Ask
View Details QP7585-ec-100ug 100ug
Recombinant Human Histone-binding protein RBBP7 Protein, His-SUMO, E.coli-100ug
Ask
View Details RC229162L1V 200 µL
C6orf134 (ATAT1) (NM_024909) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details