BCX-1898
BCX-1898, a cyclopentane derivative, is an orally active and selective influenza virus neuraminidase inhibitor. BCX-1898 has antiviral activity with EC50s of [1][2].
Product Specifications
CAS Number
345267-14-3
UNSPSC
12352211
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bcx-1898.html
Solubility
10 mM in DMSO
Smiles
CCCC(CCC)[C@@H]([C@]1([H])[C@@H](C[C@@H](C1)C(O)=O)NC(N)=N)NC(C)=O
Molecular Formula
C17H32N4O3
Molecular Weight
340.46
References & Citations
[1]D F Smee, et al. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activities. Antimicrob Agents Chemother. 2001 Mar;45 (3) :743-8.|[2]Pooran Chand, et al. Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo. Bioorg Med Chem. 2005 Jun 2;13 (12) :4071-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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