COX-2-IN-36
COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC50 of 0.4 μM[1][2].
Product Specifications
CAS Number
[189954-93-6]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-36.html
Solubility
10 mM in DMSO
Smiles
CC(C)OC1=C(C2=CC=C(C=C2)S(C)(=O)=O)[C@@](C)(OC1=O)CC
Molecular Formula
C17H22O5S
Molecular Weight
338.42
References & Citations
[1]Lushi Tan, et al. Practical enantioselective synthesis of a COX-2 specific inhibitor. Tetrahedron Volume 58, Issue 37, 9 September 2002, Pages 7403-7410.|[2]Yves Leblanc, et al. Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett. 2002 Nov 18;12 (22) :3317-20.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105304/COX-2-IN-36-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105304/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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