Sulopenem (sodium)
Sulopenem (sodium) (CP-70429 (sodium) ) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia[1][2][3].
Product Specifications
CAS Number
112294-81-2
Product Name Alternative
CP-70429 (sodium)
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sulopenem-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N12)=C(S[C@@H](CC3)C[S@@]3=O)S[C@]2([H])[C@@H]([C@H](O)C)C1=O)O[Na]
Molecular Formula
C12H14NNaO5S3
Molecular Weight
371.43
References & Citations
[1]Karlowsky JA, et al. In Vitro Activity of Sulopenem, an Oral Penem, against Urinary Isolates of Escherichia coli. Antimicrob Agents Chemother. 2018;63 (1) :e01832-18. Published 2018 Dec 21.|[2]Nagashima M, et al. In vitro and in vivo activities of sulopenem compared with those of imipenem and cephalosporins. Jpn J Antibiot. 1996;49 (4) :303-323.|[3]Minamimura M, et al. In vitro antibacterial activity and beta-lactamase stability of CP-70,429 a new penem antibiotic. Antimicrob Agents Chemother. 1993;37 (7) :1547-1551.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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