Delparantag
Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent. Delparantag shows ability to neutralize the anticoagulation and bleeding effects of UFH and LMWH[1][2].
Product Specifications
CAS Number
872454-31-4
Product Name Alternative
PMX-60056
UNSPSC
12352209
Target
Factor Xa
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/delparantag.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=C1NC([C@H](CCCCN)NC(C(C=C2NC([C@@H](N)CCCCN)=O)=C(C=C2)OC)=O)=O)=C(C=C1)OC)N[C@@H](CCCCN)C(NC(C=C3)=CC(C(N[C@@H](CCCCN)C(NC(C=C4)=CC(C(N)=O)=C4OC)=O)=O)=C3OC)=O
Molecular Formula
C56H79N13O12
Molecular Weight
1126.31
References & Citations
[1]Mahan CE. A 1-year drug utilization evaluation of protamine in hospitalized patients to identify possible future roles of heparin and low molecular weight heparin reversal agents. J Thromb Thrombolysis. 2014 Apr;37 (3) :271-8.|[2]Kuziej J, et al. In vivo neutralization of unfractionated heparin and low-molecular-weight heparin by a novel salicylamide derivative. Clin Appl Thromb Hemost. 2010 Aug;16 (4) :377-86.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2
Frequently Asked Questions
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