Eesperamicin A1
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
99674-26-7
UNSPSC
12352005
Target
Antibiotic; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eesperamicin-a1.html
Solubility
10 mM in DMSO
Smiles
CSSSC/C=C1C2=C(C([C@@H](O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)OC(C4=C(C=C(OC)C(OC)=C4)NC(C(OC)=C)=O)=O)[C@]\1(C#C/C=C\C#C[C@@H]2O[C@@]5([H])[C@@H]([C@H]([C@H](NO[C@H]6C[C@@H]([C@H](SC)[C@@H](C)O6)O)[C@@H](C)O5)O)O[C@@]7([H])C[C@@H]([C@@H](NC(C)C)CO7)OC)O)=O)NC(OC)=O
Molecular Formula
C59H80N4O22S4
Molecular Weight
1325.54
References & Citations
[1]Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115 (26), 12340–12345.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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