Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ifetroban

Ifetroban (BMS-180291) is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research[1][2][3][4].

Product Specifications

CAS Number

143443-90-7

Product Name Alternative

BMS-180291

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Ifetroban.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(CCC(C=CC=C1)=C1C[C@@H]2[C@H](C3=NC(C(NCCCCC)=O)=CO3)[C@@H]4O[C@H]2CC4)=O

Molecular Formula

C25H32N2O5

Molecular Weight

440.53

Precautions

H302, H315, H319, H335

References & Citations

[1]Johnson RA, et al. Effect of ifetroban, a thromboxane A2 receptor antagonist, in stroke-prone spontaneously hypertensive rats. Clin Exp Hypertens. 1996 Feb;18 (2) :171-88.|[2]Schumacher WA, et al. Antiplatelet activity of the long-acting thromboxane receptor antagonist BMS 180,291 in monkeys. Prostaglandins. 1992 Nov;44 (5) :389-97.|[3]Werfel TA, et al. Repurposing of a Thromboxane Receptor Inhibitor Based on a Novel Role in Metastasis Identified by Phenome-Wide Association Study. Mol Cancer Ther. 2020 Dec;19 (12) :2454-2464. |[4]Rosenfeld L, et al. Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist. Cardiovasc Drug Rev. 2001 Summer;19 (2) :97-115.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

TXA2/TP

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse IL-1 RL1 / ST2 ELISA Kit
orb170159 96 Tests

Mouse IL-1 RL1 / ST2 ELISA Kit

Sign In for Pricing
View Details
Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)
236580-01 100 mg

Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)

Sign In for Pricing
View Details
Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)
236580-02 250 mg

Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)

Sign In for Pricing
View Details
Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)
236580-03 1 g

Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)

Sign In for Pricing
View Details
Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)
236580-04 5 g

Boc-O-acetyl-L-serine dicyclohexylammonium salt ≥95% (HPLC)

Sign In for Pricing
View Details
Human Metallophosphoesterase MPPED2 (MPPED2) ELISA Kit
AE33064HU-01 48 Tests

Human Metallophosphoesterase MPPED2 (MPPED2) ELISA Kit

Sign In for Pricing
View Details