Terlakiren
Terlakiren (CP-80,794) is an orally active inhibitor of renin. Terlakiren inhibits the efficacy of human renin with an IC50 value of 0.7 nM. Terlakiren has potential applications in hypertension[1].
Product Specifications
CAS Number
119625-78-4
Product Name Alternative
CP-80,794
UNSPSC
12352005
Target
Renin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/terlakiren.html
Solubility
10 mM in DMSO
Smiles
CC(C)OC([C@H](O)[C@@](CC1CCCCC1)([H])NC([C@H](CSC)NC([C@@H](NC(N2CCOCC2)=O)CC3=CC=CC=C3)=O)=O)=O
Molecular Formula
C31H48N4O7S
Molecular Weight
620.80
References & Citations
[1]Fouda H, et al. Quantitative analysis by high-performance liquid chromatography atmospheric pressure chemical ionization mass spectrometry: The determination of the renin inhibitor CP-80,794 in human serum. J Am Soc Mass Spectrom. 1991 Apr;2 (2) :164-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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