PD 145065
Product Specifications
UNSPSC Description
PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pd-145065.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC1=CNC2=CC=CC=C12)=O)=O)=O)=O)[C@@H](C3C4=CC=CC=C4CCC5=CC=CC=C35)NC(C)=O
Molecular Weight
950.13
References & Citations
[1]Warner TD, et al. Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065. Br J Pharmacol. 1994 May;112(1):207-13.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105183/PD-145065-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105183/
Clinical Information
Phase 2
CAS Number
153049-49-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1324213-01 0.02 mg (E-Coli)
Recombinant Vibrio vulnificus 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
Ask
View Details 
MBS1324213-02 0.02 mg (Yeast)
Recombinant Vibrio vulnificus 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
Ask
View Details MBS1324213-03 0.1 mg (E-Coli)
Recombinant Vibrio vulnificus 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
Ask
View Details 
MBS1324213-04 0.1 mg (Yeast)
Recombinant Vibrio vulnificus 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
Ask
View Details 
MBS1324213-05 0.02 mg (Baculovirus)
Recombinant Vibrio vulnificus 2-dehydro-3-deoxyphosphooctonate aldolase (kdsA)
Ask
View Details