Vapiprost (hydrochloride)
Vapiprost hydrochloride (GR 32191 hydrochloride) is a thromboxane A2 receptor antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1x10-8 M[1].
Product Specifications
CAS Number
87248-13-3
Product Name Alternative
GR 32191 (hydrochloride)
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vapiprost-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC(CC/C=C\CC[C@@H]1[C@](N2CCCCC2)([H])[C@H](C[C@@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)O)=O.Cl
Molecular Formula
C30H40ClNO4
Molecular Weight
514.10
References & Citations
[1]Shuichi HORIE, et al. The Potent Inhibition of Vapiprost, a Novel Thromoboxane A2 Receptor Antagonist, on the Secondary Aggregation and ATP Release of Human Platelets.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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