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Vapiprost (hydrochloride)

Vapiprost hydrochloride (GR 32191 hydrochloride) is a thromboxane A2 receptor antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1x10-8 M[1].

Product Specifications

CAS Number

87248-13-3

Product Name Alternative

GR 32191 (hydrochloride)

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/vapiprost-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

OC(CC/C=C\CC[C@@H]1[C@](N2CCCCC2)([H])[C@H](C[C@@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)O)=O.Cl

Molecular Formula

C30H40ClNO4

Molecular Weight

514.10

References & Citations

[1]Shuichi HORIE, et al. The Potent Inhibition of Vapiprost, a Novel Thromoboxane A2 Receptor Antagonist, on the Secondary Aggregation and ATP Release of Human Platelets.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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