Netivudine

Netivudine is a nucleoside analogue with potent anti-varicella zoster virus activity. Netivudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[84558-93-0]

Product Name Alternative

882C87

UNSPSC

12352005

Target

HSV; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/netivudine.html

Solubility

10 mM in DMSO

Smiles

O=C1N([C@]2([H])O[C@@H]([C@H]([C@@H]2O)O)CO)C=C(C(N1)=O)C#CC

Molecular Formula

C12H14N2O6

Molecular Weight

282.25

References & Citations

[1]Fillastre JP, Godin M, Legallicier B, et al. Pharmacokinetics of netivudine, a potent anti-varicella zoster virus drug, in patients with renal impairment. J Antimicrob Chemother. 1996;37 (5) :965-974.