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(R) -PD 0325901CL

(R) -PD 0325901CL is an isomer of PD 0325901CL. PD 0325901CL is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) involved in cancer research. PD 0325901CL inhibits the growth of cancer cells in vitro and in vivo[1].

Product Specifications

CAS Number

[1003216-77-0]

UNSPSC

12352005

Target

MEK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-pd-0325901cl.html

Solubility

10 mM in DMSO

Smiles

O=C(NOC[C@H](O)CO)C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2Cl

Molecular Formula

C16H14ClF2IN2O4

Molecular Weight

498.65

References & Citations

[1]Bain J, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408 (3) :297-315.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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