Pomaglumetad methionil
Pomaglumetad methionil (LY2140023 hydrate) is an oral methionine prodrug of the potent specific mGlu2/3 receptor agonist LY404039 (HY-50906) . Pomaglumetad methionil is well-tolerated and has a distinct safety profile, and can be used for schizophrenia[1][2].
Product Specifications
CAS Number
[956385-05-0]
Product Name Alternative
LY2140023 (hydrate)
UNSPSC
12352005
Hazard Statement
H312-H361-H372
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pomaglumetad-methionil.html
Solubility
10 mM in DMSO
Smiles
O=C([C@]1(NC([C@@H](N)CCSC)=O)CS([C@@]2([H])[C@H](C(O)=O)[C@@]12[H])(=O)=O)O.O
Molecular Formula
C12H20N2O8S2
Molecular Weight
384.43
Precautions
P260-P264-P270-P280-P302+P352-P362+P364-P405-P501
References & Citations
₂/₃
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
MGluR2; mGluR3
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