ST 1535
ST 1535 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson’s disease[1][2].
Product Specifications
CAS Number
496955-42-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/st-1535.html
Purity
99.80
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CN1C(N2N=CC=N2)=NC3=C1N=C(CCCC)N=C3N
Molecular Formula
C12H16N8
Molecular Weight
272.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Stasi MA, et al. ST 1535: a preferential A2A adenosine receptor antagonist. Int J Neuropsychopharmacol. 2006 Oct;9 (5) :575-84.|[2]Tronci E, et al. Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: acute and subchronic studies in rats. Eur J Pharmacol. 2007 Jul 2;566 (1-3) :94-102.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A2A receptor (A2AR)
Available Sizes
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