Capsaicin-d3

Capsaicin-d3 is the deuterium labeled Capsaicin. Capsaicin ((E) -Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory and anti-cancer effects[1][2].

Product Specifications

CAS Number

[1217899-52-9]

Product Name Alternative

(E) -Capsaicin-d3

UNSPSC

12352005

Hazard Statement

H301

Target

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; TRP Channel

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

CC(C)/C=C/CCCCC(NCC1=CC(OC([2H])([2H])[2H])=C(C=C1)O)=O

Molecular Formula

C18H24D3NO3

Molecular Weight

308.43

Precautions

H301

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Anandakumar P, et al. Capsaicin provokes apoptosis and restricts benzo (a) pyrene induced lung tumorigenesis in Swiss albino mice. Int Immunopharmacol. 2013 Jun 6;17 (2) :254-259.|[3]Shin YH, et al. The Effect of Capsaicin on Salivary Gland Dysfunction. Molecules. 2016 Jun 25;21 (7) .|[4]McNamara FN, et al. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) . Br J Pharmacol. 2005 Mar;144 (6) :781-90.