SU 5402 (GMP)
SU 5402 (GMP) is SU 5402 produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively[1].
Product Specifications
CAS Number
215543-92-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
EGFR; PDGFR; VEGFR
Type
GMP Small Molecules
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/su-5402-gmp.html
Solubility
10 mM in DMSO
Smiles
O=C(CCC1=C(NC=C1C)/C=C2C(NC3=C\2C=CC=C3)=O)O
Molecular Formula
C17H16N2O3
Molecular Weight
296.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; PDGFRβ; VEGFR2/KDR/Flk-1
Frequently Asked Questions
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