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Raseglurant (hydrochloride)

Raseglurant hydrochloride is a negative allosteric modulator of mGluR5. Raseglurant hydrochloride can be used in study migraine[1].

Product Specifications

CAS Number

757949-98-7

Product Name Alternative

ADX-10059 (hydrochloride)

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/raseglurant-hydrochloride.html

Concentration

10mM

Purity

99.69

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2.[H]Cl

Molecular Formula

C15H14ClFN2

Molecular Weight

276.74

References & Citations

[1]Marin JC, et al. Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine? Expert Opin Investig Drugs. 2010 Apr;19 (4) :555-61.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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