Raseglurant (hydrochloride)
Raseglurant hydrochloride is a negative allosteric modulator of mGluR5. Raseglurant hydrochloride can be used in study migraine[1].
Product Specifications
CAS Number
[757949-98-7]
Product Name Alternative
ADX-10059 (hydrochloride)
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/raseglurant-hydrochloride.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2.[H]Cl
Molecular Formula
C15H14ClFN2
Molecular Weight
276.74
References & Citations
[1]Marin JC, et al. Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine? Expert Opin Investig Drugs. 2010 Apr;19 (4) :555-61.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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