VU 0360223
VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].
Product Specifications
CAS Number
1274859-33-4
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu-0360223.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C2=CC=C(SC(C)=N3)C3=C2)=CC(F)=C1
Molecular Formula
C15H9FN2S
Molecular Weight
268.31
References & Citations
[1]Pomierny-Chamioło L, et al. Metabotropic glutamatergic receptors and their ligands in drug addiction. Pharmacol Ther. 2014 Jun;142 (3) :281-305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RDL-1000 1000pcs/bag, 5bags/ctn
1000μl Rainin filtered pipette tips, bagged
Sign In for Pricing
View Details VAng-Lsx00709-50gEcoli 50 µg (E. coli)
Recombinant Clostridium Perfringens rex Protein (aa 1-212)
Sign In for Pricing
View Details