(±) -LY395756
(±) -LY395756 is an agonist of mGlu2 receptor and an antagonist of mGlu3 receptor. (±) -LY395756 can distinguish the native mGlu2 and mGlu3 receptors[1].
Product Specifications
CAS Number
[852679-66-4]
UNSPSC
12352211
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-ly395756.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])[C@H](C)C1)O
Molecular Formula
C9H13NO4
Molecular Weight
199.20
References & Citations
[1]Ceolin L, et al. Study of novel selective mGlu2 agonist in the temporo-ammonic input to CA1 neurons reveals reduced mGlu2 receptor expression in a Wistar substrain with an anxiety-like phenotype. J Neurosci. 2011 May 4;31 (18) :6721-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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