Galnon
Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].
Product Specifications
CAS Number
475115-35-6
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/galnon.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N[C@@H](CCCCN)C(NC1=CC=C(C(C)=C2)C(OC2=O)=C1)=O)=O)CC3CCCCC3)OCC4C5=CC=CC=C5C6=CC=CC=C46
Molecular Formula
C40H46N4O6
Molecular Weight
678.82
References & Citations
[1]Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101 (28) :10470-5.|[2]Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41 (5) :307-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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