DPNI-GABA
DPNI-GABA is a nitroindoline cage compound that inhibits GABA (A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM[1].
Product Specifications
CAS Number
[927866-58-8]
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dpni-gaba.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC(COP(O)(O)=O)COP(O)(O)=O)CCCN
Molecular Formula
C15H23N3O12P2
Molecular Weight
499.30
References & Citations
[1]Trigo FF, et al. Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J Neurosci Methods. 2009 Jul 30;181 (2) :159-69.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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