SB-205384
SB-205384 is a GABAA receptor modulator. The primary effect of SB-205384 on GABAA-activated currents is a prolonged response decay half-life upon removal of the agonist[1].
Product Specifications
CAS Number
[160296-13-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-205384.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)N=C2C(C3=C(CC(O)CC3)S2)=C1N)OCC#CC
Molecular Formula
C17H18N2O3S
Molecular Weight
330.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Meadows HJ, et al. Effect of SB-205384 on the decay of GABA-activated chloride currents in granule cells cultured from rat cerebellum. Br J Pharmacol. 1997 Aug;121 (7) :1334-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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