Ro19-4603
Ro19-4603 is a benzodiazepine inverse agonist. Ro19-4603 antagonizes ethanol (EtOH) intake in alcohol-preferring rats[1].
Product Specifications
CAS Number
99632-94-7
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro19-4603.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(CN2C)N(C=N1)C(C=CS3)=C3C2=O)OC(C)(C)C
Molecular Formula
C15H17N3O3S
Molecular Weight
319.38
References & Citations
[1]June HL, et al. The benzodiazepine inverse agonist RO19-4603 exerts prolonged and selective suppression of ethanol intake in alcohol-preferring (P) rats. Psychopharmacology (Berl) . 1994 Jul;115 (3) :325-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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