U-89843A (hydrochloride)
U-89843A is an allosteric modulator of GABAA receptor. U-89843A enhances GABA-induced Cl- currents[1].
Product Specifications
CAS Number
[157013-85-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/u-89843a-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CN1C(C)=CC2=C(N3CCCC3)N=C(N4CCCC4)N=C21.[H]Cl
Molecular Formula
C16H24ClN5
Molecular Weight
321.85
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Im HK, Im WB, et al. U-89843A is a novel allosteric modulator of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1995 Dec;275 (3) :1390-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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